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[Bacteremia caused by beta-hemolytic group A streptococci].
J Begovac1, B Gmajnicki, N Kuzmanović
1Klinika za infektivne bolesti, Dr. Fran Mihaljević, Zagreb.
Lijecnicki Vjesnik
|November 1, 1991
Summary
Group A beta-hemolytic streptococcal (GABHS) bacteremia can cause severe infections, particularly in children. Prompt recognition and treatment are crucial due to potential changes in GABHS virulence.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Context:
- Group A beta-hemolytic streptococcal (GABHS) bacteremia is a serious infection.
- Analysis of 51 cases over 15 years at a specialized infectious diseases hospital.
- Increasing incidence observed since 1987.
Purpose:
- To analyze the epidemiological, clinical, and laboratory characteristics of GABHS bacteremia.
- To identify risk factors and outcomes associated with GABHS bacteremia.
- To assess potential changes in GABHS virulence.
Summary:
- The study analyzed 51 cases of GABHS bacteremia, with a mean patient age of 25 years (57% under 18).
- Mortality was 19%, with 6 deaths in patients under 18. Community-acquired infections (92%) and underlying diseases (32%) were common.
- Primary infection sites included pharyngitis and erysipelas/cellulitis. Shock was associated with all fatalities.
Impact:
- Highlights the potential for severe GABHS infections in children, even those previously healthy.
- Emphasizes the need for prompt recognition and treatment of GABHS bacteremia.
- Suggests a possible worldwide increase in GABHS virulence, necessitating further investigation.