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Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents

Roland W Bürli1, Han Xu, Xiaoming Zou

  • 1Chemistry Research and Discovery, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA. rburli@amgen.com

Bioorganic & Medicinal Chemistry Letters
|May 16, 2006
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Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...