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Updated: Aug 8, 2026

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization
Published on: August 11, 2018
Host defence peptides from invertebrates--emerging antimicrobial strategies
Robert E W Hancock1, Kelly L Brown, Neeloffer Mookherjee
1Department of Microbiology and Immunology, University of British Columbia, 2259 Lower Mall, Vancouver, BC, Canada V6T 1Z4. bob@cmdr.ubc.ca
Abstract:
Cationic antimicrobial (host defence) peptides are found as potent components of the innate immune system of all invertebrates in which they have been investigated. They vary substantially in their amino acid sequences, secondary structures, inducibility, potency and antimicrobial activity spectra. This enormous diversity is providing templates for the design and development of both antibiotic peptides and peptides that selectively modulate innate immunity to increase protection against infections and sepsis.
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