Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anatomy changes in radiotherapy detected using portal imaging.

Leah N McDermott1, Markus Wendling, Jan-Jakob Sonke

  • 1Department of Radiation Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
|May 16, 2006
PubMed
Summary

Anatomical changes detected in weekly radiotherapy localisation images can significantly alter radiation doses. Difference imaging effectively identifies these changes, prompting re-planning to ensure accurate treatment delivery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical feasibility of fast adaptive four-dimensional cone-beam computed tomography for lung cancer radiotherapy.

Physics and imaging in radiation oncology·2026
Same author

Simultaneous concurrent chemoradiation and SBRT in stage III NSCLC: Safety report of the phase I hybrid trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Estimation of accumulated dose to organs at risk in head and neck cancer patients treated with scheduled replanning and dose painting in the ARTFORCE trial.

Physics and imaging in radiation oncology·2026
Same author

Dose-based evaluation of delineation variation in radiotherapy: A scoping review.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Acute and long-term toxicity profiles and final oncologic outcomes in the phase III ARTFORCE trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Automated target misalignment correction for cone beam computed tomography-based online adaptive radiotherapy of locally advanced lung cancer patients.

Physics and imaging in radiation oncology·2025

Area of Science:

  • Radiation Oncology
  • Medical Imaging
  • Radiotherapy Physics

Background:

  • Localisation images in radiotherapy verification contain anatomical data.
  • Investigating anatomical changes and dosimetric consequences from these images is crucial.

Observation:

  • Weekly electronic portal imaging device (EPID) localisation images were analyzed.
  • Difference images were created by subtracting initial images from subsequent ones.
  • 81 lung, 40 head and neck, and 34 prostate cancer patients' images were classified.

Findings:

  • Progressive anatomical changes occurred in 57% of lung and 37% of head and neck cancer patients.
  • Random changes were noted in 37% lung, 28% head and neck, and 82% prostate cancer patients.
  • Tumour shrinkage in lung cancer increased EPID dose by 10.0%, raising mean lung dose by 9.8%.

Related Experiment Videos

  • Rectal gas pockets in prostate cancer increased EPID dose by 6.3% and decreased PTV minimum dose by 26.4%.

    • Implications:

    • Difference imaging is an efficient method for detecting anatomical changes during radiotherapy.
    • This technique can identify if delivered radiation dose deviates from the planned dose.
    • It helps determine the need for treatment re-planning to maintain therapeutic accuracy.