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Ectopic uterine ovarian tissue in cynomolgus monkeys

Yuki Kuwamura1, Kimiyo Kakehi, Kimiaki Hirakawa

  • 1Pathology Center, Drug Safety Research Laboratories, Shin Nippon Biomedical Laboratories, Ltd., Osaka 541-0044, Japan. Kuwamura-yuki@snbl.co.jp

Toxicologic Pathology
|May 16, 2006
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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...