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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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Observations of amino acid gain and loss during protein evolution are explained by statistical bias

Richard A Goldstein1, David D Pollock

  • 1Division of Mathematical Biology, National Institute of Medical Research, Mill Hill, London, United Kingdom. richard.goldstein@nimr.mrc.ac.uk

Molecular Biology and Evolution
|May 16, 2006
PubMed

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