Depression, physical impairment, and treatment of depression in chronic heart failure

Carolyn L Turvey1, Dawn M Klein, Carla J Pies

  • 1Department of Psychiatry, University of Iowa, Iowa City, Iowa 52242-1000, USA. Carolyn-Turvey@uiowa.edu

Insights

Patient attitudes toward impairment significantly influence depression in heart failure patients. Addressing emotional adjustment to physical limitations is key for managing chronic depressive symptoms.

Area of Science:

  • Cardiology
  • Psychiatry
  • Rehabilitation Medicine

Background:

  • Heart failure (HF) is frequently comorbid with depression.
  • Depression in HF patients is linked to physical impairment.
  • The role of patient attitudes in this relationship requires further investigation.

Purpose of the Study:

  • To examine how attitudes about impairment mediate the link between depression and physical impairment in heart failure patients.
  • To assess the current use of antidepressant treatments in outpatients with heart failure.

Main Methods:

  • 32 depressed and 51 non-depressed heart failure outpatients were enrolled.
  • Baseline assessments included medical, functional, cognitive, and psychological measures.
  • Depression was reassessed in the depressed cohort at 8, 16, and 24 weeks.

Main Results:

  • Attitudes about impairment and social support were strong correlates of depression.
  • The association between physical impairment and depression diminished when attitudes about impairment were controlled.
  • Attitudes about impairment predicted the persistence of depressive symptoms over time.

Conclusions:

  • The relationship between physical impairment and depression in heart failure is moderated by patients' coping mechanisms and attitudes.
  • Interventions targeting emotional adjustment to physical impairment are needed for treating depression in heart failure.
  • Current antidepressant treatment status in this population was also described.
Abstract

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