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Depression, physical impairment, and treatment of depression in chronic heart failure
Carolyn L Turvey1, Dawn M Klein, Carla J Pies
1Department of Psychiatry, University of Iowa, Iowa City, Iowa 52242-1000, USA. Carolyn-Turvey@uiowa.edu
Insights
Patient attitudes toward impairment significantly influence depression in heart failure patients. Addressing emotional adjustment to physical limitations is key for managing chronic depressive symptoms.
Area of Science:
- Cardiology
- Psychiatry
- Rehabilitation Medicine
Background:
- Heart failure (HF) is frequently comorbid with depression.
- Depression in HF patients is linked to physical impairment.
- The role of patient attitudes in this relationship requires further investigation.
Purpose of the Study:
- To examine how attitudes about impairment mediate the link between depression and physical impairment in heart failure patients.
- To assess the current use of antidepressant treatments in outpatients with heart failure.
Main Methods:
- 32 depressed and 51 non-depressed heart failure outpatients were enrolled.
- Baseline assessments included medical, functional, cognitive, and psychological measures.
- Depression was reassessed in the depressed cohort at 8, 16, and 24 weeks.
Main Results:
- Attitudes about impairment and social support were strong correlates of depression.
- The association between physical impairment and depression diminished when attitudes about impairment were controlled.
- Attitudes about impairment predicted the persistence of depressive symptoms over time.
Conclusions:
- The relationship between physical impairment and depression in heart failure is moderated by patients' coping mechanisms and attitudes.
- Interventions targeting emotional adjustment to physical impairment are needed for treating depression in heart failure.
- Current antidepressant treatment status in this population was also described.
Background And Research Objective:
This study examines the contribution of attitudes about impairment to the relation between depression and physical impairment in patients with heart failure. It also describes the current status of antidepressant treatment in a sample of outpatients with heart failure.
Subjects And Methods:
A total of 32 depressed and 51 nondepressed patients with heart failure were recruited while seeking heart failure treatment in an outpatient heart failure or family practice clinic. Medical, functional, cognitive, and psychological measures were administered at baseline. Depression measures were readministered to the 32 depressed patients at 8, 16, and 24 weeks after the baseline interview.
Results And Conclusions:
Attitudes about impairment and perceived social support were the strongest cross-sectional correlates of depression. The strong association between physical impairment and depression was no longer significant after controlling for attitudes about impairment. In addition, attitudes about impairment predicted chronicity of depressive symptoms longitudinally after controlling for baseline depressive symptom severity. The relation between physical impairment and depression in heart failure is strongly related to how patients cope with impairment. These results call for the development of additional interventions to treat depression that focus on the emotional adjustment to physical impairment.
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