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Related Experiment Videos

Acitretin induced bipedal edema.

Hong Liang Tey1, Thiam Seng Colin Theng

  • 1National Skin Center, Singapore.

The Journal of Dermatology
|May 17, 2006
PubMed
Summary
This summary is machine-generated.

Localized leg swelling is a rare side effect of systemic retinoids like acitretin. This case study details a patient experiencing bipedal edema, which resolved after discontinuing acitretin.

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Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Systemic retinoids are used for various dermatological conditions.
  • Generalized edema is a known, albeit rare, side effect of systemic retinoid therapy.

Observation:

  • A patient presented with localized bipedal edema.
  • The edema was attributed to acitretin, a systemic retinoid.
  • Other potential causes of edema were ruled out.

Findings:

  • Acitretin treatment led to the development of localized bipedal edema.
  • Discontinuation of acitretin resulted in the complete resolution of the edema.

Implications:

  • This case highlights localized bipedal edema as a potential, rare adverse effect of acitretin.

Related Experiment Videos

  • Clinicians should consider acitretin-induced edema in patients presenting with unexplained leg swelling.
  • Monitoring for peripheral edema is recommended during acitretin therapy.