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Multiple receptors mediate the trophic effects of serotonin on ventroposterior thalamic neurons in vitro

Antonio M Persico1, Giovanni Di Pino, Pat Levitt

  • 1Laboratory of Molecular Psychiatry and Neurogenetics, University Campus Bio-Medico, Via Emilio Longoni 83, I-00155 Rome, Italy. a.persico@unicampus.it

Brain Research
|May 17, 2006
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G-protein Coupled Receptors

G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.