[Molecular biology of pathogenesis by herpesvirus]

A distinguishing feature of Herpes simplex virus (HSV) infections is the ability of these viruses to persist for long periods in their host in nonreplicative or latent state. The study of pathogenesis of herpesvirus infections can be divided in: acute viral replication, establishment of latency, maintenance of latency and reactivation. In this paper we analyzed the viral genetic information which was identified as essential or very important for such events.