Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cutaneous microdialysis: is it worth the sweat?

Chris D Anderson1

  • 1Department of Dermatology, Linköping University, Linköping, Sweden. Chris.Anderson@lio.se

The Journal of Investigative Dermatology
|May 17, 2006
PubMed
Summary

Microdialysis, a minimally invasive technique, studies metabolic and biochemical events in living skin tissue. Advances are expanding its applications in percutaneous penetration and inflammation research.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Non-invasive tape sampling of tryptophan and kynurenine in relation to phenylalanine and tyrosine from melanoma and adjacent non-lesional skin: A pilot study.

PloS one·2025
Same author

Successful Photodynamic Treatment of a Pigmented Nodular BCC Using a Biphasic Activation Protocol.

The Australasian journal of dermatology·2025
Same author

The Effect of Repeated Capillary Refill Tests on the Cutaneous Microcirculation.

Journal of biophotonics·2024
Same author

Evaluation of an artificial intelligence-based decision support for the detection of cutaneous melanoma in primary care: a prospective real-life clinical trial.

The British journal of dermatology·2024
Same author

Establishment and Utility of SwedAD: A Nationwide Swedish Registry for Patients with Atopic Dermatitis Receiving Systemic Pharmacotherapy.

Acta dermato-venereologica·2023
Same author

Treatment Patterns among Patients with Atopic Dermatitis in Secondary Care: A National, Observational, Non-interventional, Retrospective Study in Sweden.

Acta dermato-venereologica·2022

Area of Science:

  • Dermatology and Pharmacology
  • Biomedical Engineering

Background:

  • Microdialysis is a minimally invasive method for real-time analysis of biochemical and metabolic processes in living tissues.
  • In dermatological research, microdialysis probes are inserted into the dermis or subcutis to investigate skin physiology and pathology.

Discussion:

  • The technique is pivotal for studying percutaneous penetration, understanding how substances traverse the skin barrier.
  • It also plays a crucial role in elucidating the complex mechanisms of skin inflammation.
  • Ongoing advancements in microdialysis methodology and data analysis are broadening its research scope.

Key Insights:

  • Microdialysis enables chronological monitoring of metabolic, biochemical, and pharmacological events directly within skin tissue.
  • It provides valuable data for research on drug delivery, skin absorption, and inflammatory responses.
  • The technique's minimally invasive nature allows for repeated sampling and longitudinal studies.

Outlook:

  • Future applications may include personalized medicine, advanced wound healing studies, and in-situ assessment of cosmetic product efficacy.
  • Integration with advanced imaging and analytical techniques promises deeper insights into skin biology.
  • Further refinement of probe technology and data interpretation will enhance its utility in diverse research fields.

Related Experiment Videos