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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Hyperacute unilateral gonococcal endophthalmitis in an HIV-infected man without genital infection
F Faggian1, A Azzini, M Lanzafame
1Infectious Diseases Unit, Ospedale Civile Maggiore, Verona, Italy. ffaggian@hotmail.com
Purpose:
To demonstrate the necessity of obtaining an accurate history from patients presenting abnormal evolution of ophthalmologic diseases.
Methods:
A 42-year-old patient, denying any previous ocular or systemic morbidity, presented with an unusual severe and hyperacute gonococcal endophthalmitis with corneal abscess but no concurrent genitourinary infection. Only after a further interview did the patient reveal his human immunodeficiency virus status and a previous diagnosis of acquired immunodeficiency syndrome.
Results:
Adequate topical and intravenous antibiotic treatment and surgery led to salvage of the eye.
Conclusions:
An accurate history should be obtained by patients with an abnormal course of an ophthalmologic disease, focusing on immunologic deficiencies that can cause extremely serious ophthalmologic complications with ensuing risk of visual impairment or ocular loss (bulbar enucleation).
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