Related Experiment Video
Updated: Aug 8, 2026

Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
Published on: March 10, 2020
[Diarrhoea-causing agents in children aged less than five in Tunja, Colombia]
Fred G Manrique-Abril1, Billon Tigne y Diane, Sandra E Bello
1Escuela de Medicina-Enfermería Universidad Pedagógica y Tecnológica de Columbia. gisp@tunja.uptc.edu.co
Insights
Rotavirus is the primary cause of acute diarrhea in children under five in Tunja, Colombia. This study identified infectious agents responsible for acute diarrhea disease (ADD) in young children.
Area of Science:
- Pediatric Infectious Diseases
- Gastroenterology
- Microbiology
Background:
- Acute diarrhea disease (ADD) is a significant health concern in young children globally.
- Identifying causative infectious agents is crucial for effective prevention and treatment strategies.
- Previous studies have indicated various pathogens contribute to ADD in different regions.
Purpose of the Study:
- To determine the prevalence and types of infectious agents causing ADD in children under five.
- To analyze the association between specific pathogens and age in affected children.
- To provide epidemiological data on infectious diarrhea in Tunja, Colombia.
Main Methods:
- A cross-sectional study was conducted involving 129 children under five with ADD.
- Fecal samples were collected from children attending outpatient consultations.
- Samples were analyzed to identify infectious agents including Rotavirus, Shigella, E. coli, Campylobacter, Giardia lamblia, and E. histolytica.
Main Results:
- Rotavirus was the most prevalent agent, found in 48.1% of cases.
- Other identified agents included E. coli (13.9%), Giardia lamblia (12.4%), E. histolytica (7%), Campylobacter (2.3%), and Shigella (0.8%).
- The prevalence of Rotavirus, E. coli, and Campylobacter showed a statistically significant increase with age.
Conclusions:
- Rotavirus is identified as the leading cause of acute diarrhea disease in children under five in the studied population.
- The prevalence of identified agents aligns with findings from other Colombian and Latin American studies.
- These findings underscore the importance of Rotavirus vaccination and targeted interventions for infectious diarrhea.
Objectives:
Determining the prevalence and type of infectious ADD-causing agents in a sample of children aged less than five who consulted the IPS in Tunja during 2004.
Material And Methods:
A cross-sectional study was designed. Data was obtained by surveying 129 children younger than 5 suffering from ADD. Samples of faeces were obtained following outpatient consultation at San Rafael Hospital and SaludCoop's clinic in Tunja.
Results:
Rotavirus was found in 48.1% of cases, Shigella in 0.8%, E. coli in 13.9%, Campylobacter in 2.3%, Giardia lamblia in 12.4% and E. hitolytica in 7%. The causative agent could not be identified in 15.5% of cases. The statistical association grew with age for Rotavirus (p < 0.01), E. coli (p < 0.05) and campylobacter (p < 0.001).
Conclusion:
Rotavirus is the major causative agent of ADD in children younger than one year and, generally, in children aged less than five. The prevalence found was similar to data reported in studies carried out in Facatatativá, Bogotá, Santander, Manizales and the Chocó in Colombia and studies carried out in Venezuela, Peru and Mexico.
Related Concept Videos
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Cholera
Bacterial Gastroenteritis
Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents
Adsorbents...
Giardiasis
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
