[Immunohistochemical study of heme oxygenase-1 expressed in human normal dental pulp cell and tissue]
Fan Yang1, Zhen-Yu Hu, Hao Fang
1Dept. of Stomatology, Medical College of Zhejiang University, Hangzhou 310006, China.
Objective:
To study the expression of heme oxygenase-1 (HO-1) in dental pulp tissue and to find out the relationship of distribution and function of HO-1.
Methods:
30 pulp tissues were obtained from clinically extracted human healthy premolars and third molars. The expression of HO-1 in dental pulp was detected by means of SABC immunohistochemical technology.
Results:
HO-1 immunoreactivity was observed in vascular endothelial cells, odontoblasts and some fibroblasts cells.
Conclusion:
The distribution of HO-1 in normal human dental pulp suggests that HO-1 may play an important role in pulp flow regulation, dentin production and its calcifying; it also may play some roles in dental pulp cells metabolism and differentiation.
