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Related Experiment Videos

Whose data set is it anyway? Sharing raw data from randomized trials.

Andrew J Vickers1

  • 1Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, NY, USA. vickersa@mskcc.org

Trials
|May 18, 2006
PubMed
Summary
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Sharing raw clinical trial data benefits research reproducibility and patient care. Making data accessible, like publishing online, is crucial for scientific integrity and public trust.

Area of Science:

  • Medical Research
  • Clinical Trials
  • Genomics

Background:

  • Raw data sharing is standard in many medical fields, yet clinical trial investigators often withhold data.
  • Concerns about being scooped or work misrepresented hinder data sharing among trialists.

Discussion:

  • Data sharing enhances research by enabling analysis reproduction, secondary hypothesis testing, and new method development.
  • Simple measures like co-authorship can mitigate concerns about intellectual property and misrepresentation.
  • Viewing data as belonging to patients, not investigators, reframes data sharing benefits.

Key Insights:

  • Internet technologies have simplified the logistics of data sharing.
  • Data sharing should be an integral part of conducting randomized trials, akin to ethical review.

Related Experiment Videos

  • Journals and funders should mandate raw data availability, such as via web publication.

    • Outlook:

    • Failure to share data risks public perception that trials serve researchers, not patients.
    • Promoting data sharing fosters transparency and accelerates medical advancements.
    • Standardizing data sharing practices will improve the rigor and impact of clinical research.