Emerging pediatric HIV epidemic related to migration
Related Experiment Video
Updated: Aug 8, 2026

New Tools to Expand Regulatory T Cells from HIV-1-infected Individuals
Published on: May 30, 2013
Douglas W MacPherson1, Militza Zencovich, Brian D Gushulak
1Migration Health Consultants Inc., Cheltenham, Ontario, Canada. douglaswmacpherson@migrationhealth.com
Insights
Canada
Area of Science:
- Public Health
- Infectious Diseases
- Immigration Health
Background:
- Canada implemented mandatory HIV screening for residency applicants in 2002.
- Screening included selected children immigrating to Canada.
Purpose of the Study:
- To report on the findings of mandatory HIV screening for child immigrants.
- To assess the implications of HIV detection in this population.
Main Methods:
- Analysis of HIV screening results from January 2002 to February 2005.
- Data collection on pediatric HIV cases among residency applicants.
Main Results:
- 36 pediatric HIV cases were detected (14/100,000 applicants).
- 94% of infected children were eligible for immigration, primarily from Africa.
- Maternal infection was the primary risk factor; only 11% received antiretroviral therapy.
Conclusions:
- HIV-infected immigrant children represent a potential emerging epidemic in low-incidence countries.
- Early identification of HIV-infected immigrant women is crucial for preventing mother-to-child transmission.
- Routine HIV testing for immigrants has significant health policy implications.
Abstract:
In 2002, Canada introduced routine, mandatory HIV antibody screening for all residency applicants, including selected children. We report screening results from January 2002 to February 2005. Thirty-six pediatric HIV cases were detected (14/100,000 applicants); 94% of infected children were eligible to arrive in Canada. Thirty-two of the affected children were from Africa, and maternal infection was the main risk factor. Only 4 (11%) of the children had received antiretroviral therapy. In countries of low HIV incidence, migration-related imported infection in children may be an emerging epidemic. The early identification of HIV-infected immigrant women permits intervention to prevent mother-to-child HIV transmission. Routine HIV testing as a component of the medical examination of immigrants has national and international health policy and programmatic implications.
Related Concept Videos
Amebiasis
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Sexually Transmitted Infections
Transmission of Pathogens
Malaria