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Using a Pan-Viral Microarray Assay (Virochip) to Screen Clinical Samples for Viral Pathogens
Published on: April 27, 2011
[The research and development of new diagnostic gene chips for SARS coronavirus]
Jianhua Lai1, Zhiqin Zhang, Ming Yu
1Laboratory of Biochemistry & Molecule Biology, School of Life Sciences, Yunnan University, Kunming 650091, China.
Abstract:
The loci of cDNA sequences for valid diagnosis have been identified through the selection of the genome of SARS coronaries. The gene chips for diagnosing such virus have been developed, based on our own-developed technology for manufacturing and application of gene chips. The diagnoses given by such gene chips were consistent well with the reports of clinical laboratories (94.29%) and the sensitivity reached 10(-2)/ml virus molecules. This method is well suited for the clinical use in SARS coronaries diagnosis.
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