Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ecological and evolutionary principles in immunology.

Dominik Wodarz1

  • 1Department of Ecology and Evolutionary Biology, 321 Steinhaus Hall, University of California, Irvine, CA 92697, USA. dwodarz@uci.edu

Ecology Letters
|May 19, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Population structure reverses selection of variants with proportionally scaled birth and death rates.

Nature communications·2025
Same author

Author Correction: Barcoded HIV-1 reveals viral persistence driven by clonal proliferation and distinct epigenetic patterns.

Nature communications·2025
Same author

Efficient mathematical methodology to determine multistep mutant burden in spatially growing cell populations.

PNAS nexus·2025
Same author

Post-transfusion activation of coagulation pathways during severe COVID-19 correlates with COVID-19 convalescent plasma antibody profiles.

The Journal of clinical investigation·2025
Same author

Compartmental structure in the secondary lymphoid tissue can slow down <i>in vivo</i> HIV-1 evolution in the presence of strong CTL responses.

Journal of the Royal Society, Interface·2025
Same author

Deuterated water labeling in ibrutinib-treated patients with CLL: leukemia cell kinetics correlate with IGHV, ZAP-70, and MRD.

Blood·2024

This review applies ecological and evolutionary principles to immunology, viewing host-pathogen interactions as an in vivo ecosystem. Understanding concepts like competition and viral evolution enhances insights into immune control and pathology.

Area of Science:

  • Immunology
  • Ecology
  • Evolutionary Biology

Background:

  • Experimental immunology details immune cell responses to pathogens.
  • Host-pathogen interactions can be modeled as in vivo ecological systems.
  • Complex dynamics exist between immune cells and pathogen populations.

Purpose of the Study:

  • To explore how ecological and evolutionary principles can enhance the understanding of the immune system.
  • To apply concepts such as competition, predation, and viral evolution to immunological contexts.
  • To elucidate key immunological phenomena through an ecological lens.

Main Methods:

  • Review of existing literature integrating ecological and evolutionary concepts with immunology.
  • Application of ecological principles (competition, predation) to immune responses.

Related Experiment Videos

  • Analysis of viral evolution in the context of host-pathogen dynamics.

    • Main Results:

    • Ecological and evolutionary frameworks provide novel perspectives on immune function.
    • These principles illuminate mechanisms of efficient virus control and immunodominance.
    • Insights gained into the relationship between viral evolution, pathology, and immune suppression.

    Conclusions:

    • An ecological-evolutionary approach offers a powerful framework for understanding complex immune responses.
    • This perspective aids in explaining phenomena like immune evasion and the development of disease.
    • The study highlights the interconnectedness of host immunity and pathogen evolution.