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Published on: January 7, 2019
The alliance against depression: 2-year evaluation of a community-based intervention to reduce suicidality
Ulrich Hegerl1, David Althaus, Armin Schmidtke
1Department of Psychiatry, Ludwig-Maximilians-University, Munich, Germany. UHegerl@med.uni-muenchen.de
Background:
The global burden and large diagnostic and therapeutic deficits associated with depressive disorders call for intervention programs. The aim of the Nuremberg Alliance against Depression (NAD) is to establish and to assess the effectiveness of a four-level intervention program for improving the care of patients with depression.
Method:
A 2-year intervention program was performed in Nuremberg (480000 inhabitants) at four levels: training of family doctors and support through different methods; a public relations campaign informing about depression; cooperation with community facilitators (teachers, priests, local media, etc.); and support for self-help activities as well as for high-risk groups. The effects of the 2-year intervention on the number of suicidal acts (completed suicides plus suicide attempts, main outcome criterion) were evaluated with respect to a 1-year baseline and a control region (Wuerzburg, 270,000 inhabitants).
Results:
Compared to the control region, a reduction in frequency of suicidal acts was observed in Nuremberg during the 2-year intervention (2001 v. 2000: -19.4%; p< or =0.082; 2002 v. 2000: -24%, p< or =0.004). Considering suicide attempts only (secondary outcome criterion), the same effect was found (2001 v. 2000: -18.3%, p< or =0.023; 2002 v. 2000: -26.5%, p<0.001). The reduction was most noticeable for high-risk methods (e.g. hanging, jumping, shooting). Concerning completed suicides, there were no significant differences compared to the control region.
Conclusions:
The NAD appeared to be effective in reducing suicidality. It provides a concept as well as many methods that are currently being implemented in several other intervention regions in Germany and in other countries.
Insights
The Nuremberg Alliance against Depression (NAD) intervention significantly reduced suicidal acts, including attempts, over two years. This program offers a scalable model for improving depression care and reducing suicide rates globally.
Area of Science:
- Public Health
- Psychiatry
- Intervention Science
Background:
- Depressive disorders represent a significant global health burden with substantial care deficits.
- Effective intervention programs are crucial for improving patient outcomes.
- The Nuremberg Alliance against Depression (NAD) initiative aimed to address these gaps.
Purpose of the Study:
- To establish a multi-level intervention program for depression care.
- To evaluate the effectiveness of the NAD intervention in reducing suicidality.
Main Methods:
- A 2-year, four-level intervention was implemented in Nuremberg, Germany.
- Intervention components included healthcare provider training, public awareness campaigns, community engagement, and support for self-help.
- Suicidal acts (completed suicides and attempts) were compared against a baseline year and a control region.
Main Results:
- A significant reduction in suicidal acts was observed in Nuremberg compared to the control region.
- Suicide attempts specifically showed a marked decrease during the intervention period.
- The reduction in suicidality was particularly pronounced for high-risk methods.
Conclusions:
- The NAD intervention demonstrated effectiveness in reducing overall suicidality.
- The program provides a transferable model for depression care interventions.
- The NAD concept is being adopted in other regions in Germany and internationally.

