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Epidermolytic hyperkeratosis with rickets.

Surajit Nayak¹, Samira Kumar Behera, Basanti Acharjya

¹Department of Dermatology, M.K.C.G. Medical College, Berhampur, Orissa, India. surajitnyk@yahoo.co.in

Indian Journal of Dermatology, Venereology and Leprology

|May 19, 2006

Summary

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This rare case highlights epidermolytic hyperkeratosis, a skin condition, co-occurring with nutritional rickets in a child. Early diagnosis and treatment with vitamin D3 and calcium are crucial for managing these combined conditions.

Area of Science:

Dermatology
Pediatrics
Biochemistry

Background:

Ichthyosis encompasses a group of genetic skin disorders characterized by dry, scaling skin.
Epidermolytic hyperkeratosis (EH) is a severe form of ichthyosis.
Nutritional rickets, a vitamin D deficiency disorder, can affect children with ichthyosis.

Observation:

A 6-year-old child presented with generalized hyperkeratosis, particularly in skin flexures.
The child also exhibited windswept deformity of the legs and limping, indicative of skeletal issues.
Clinical, histopathologic, and biochemical assessments were performed.

Findings:

The patient was diagnosed with epidermolytic hyperkeratosis and nutritional rickets.
Treatment involved parenteral vitamin D3 and oral calcium supplementation.

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This case is notable due to the rarity of co-occurrence between EH and rickets.

Implications:

This case underscores the importance of considering metabolic bone diseases like rickets in children with ichthyosis.
Early identification and management of vitamin D deficiency are critical in affected pediatric populations.
Further research into the complex interplay between genetic skin disorders and nutritional deficiencies is warranted.