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Updated: Aug 3, 2026

Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Giant cell tumor of skin
Y Sunil Kumar1, A R Raghupathi,
1Department of Pathology, Government Medical College, Mysore, Karnataka, India. drsunilkumary@rediffmail.com
Abstract:
Giant cell tumor of the skin is a rare entity showing gross and histological features similar to those of giant cell tumor of the bone. We report a case of malignant giant cell tumor of the thigh in a 55-year-old man. Histological features showed a biphasic population of mononuclear cells admixed with osteoclast-like giant cells. The nuclei of the giant cells were similar to those of the mononuclear cells. This tumor should be distinguished from a variety of cutaneous neoplasms that contain multinucleated giant cells.
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