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Published on: September 30, 2021

Successful treatment of life-threatening bleeding after cesarean section with recombinant activated factor VII

L Heilmann1, C Wild, B Hojnacki

  • 1Department of Obstetrics and Gynecology, City Hospital Rüsselsheim, Germany. dr_lothar_heilmann@yahoo.de

Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
|May 19, 2006
PubMed

Hemorrhagic shock developed in a 29-year-old nullipara without coagulopathy after emergency caesarean section. Treatment with uterotonic drugs, prostaglandins, and conservative procedures with transfusion of packed red cells and fresh-frozen plasma failed to control the diffuse vaginal and uterine bleeding. Finally an intravenous bolus injection of 90 microg/kg recombinant activated factor VII (rFVIIa, NovoSeven, Novo Nordisk A/S, Bagsvaerd, Denmark), was given and showed success within 20 minutes after administration, without any side effects.

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