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Does a multifaceted environmental intervention alter the impact of asthma on inner-city children?
Seymour G Williams1, Clive M Brown, Kenneth H Falter
1National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. sjw9@cdc.gov
Insights
A multifaceted intervention reduced dust mite allergen levels and improved asthma functional severity scores in urban children. This environmental and educational approach showed promise despite challenges in participant retention.
Area of Science:
- Environmental health
- Pediatric asthma management
- Allergen control
Background:
- Urban children with asthma face significant indoor environmental triggers.
- Multifaceted interventions are being explored to mitigate asthma severity.
Purpose of the Study:
- To assess the impact of an environmental and educational intervention on indoor allergens and asthma health in urban children aged 5-12.
- To compare outcomes between an intervention group and a delayed intervention control group.
Main Methods:
- A 14-month prospective field trial involving randomized controlled design.
- Intervention included dust mite covers, professional cleaning, and pest control.
- Asthma severity, allergen levels, and healthcare utilization were measured.
Main Results:
- Dust mite levels increased significantly in the delayed intervention group.
- Overall asthma severity scores did not change, but functional severity scores (FSS) improved.
- The intervention group showed a significant improvement in median FSS (25%) compared to the control group (p<0.01).
Conclusions:
- The intervention effectively reduced dust mite allergen levels and improved FSS in children with asthma.
- Despite low retention rates, the intervention demonstrated positive effects, particularly for more severely affected children.
- Complexities in intervention design and outcome assessment for multifaceted asthma programs were highlighted.
Objective:
To evaluate the impact of a multifaceted environmental and educational intervention on the indoor environment and health in 5-12-year-old children with asthma living in urban environments.
Design:
Changes in indoor allergen levels and asthma severity measurements were compared between children who were randomized to intervention and delayed intervention groups in a 14-month prospective field trial. Intervention group households received dust mite covers, a professional house cleaning, and had roach bait and trays placed in their houses.
Results:
Of 981 eligible children, 410 (42%) were enrolled; 161 (40%) completed baseline activities and were randomized: 84 to intervention and 77 to delayed intervention groups. At the study's end, dust mite levels were 163% higher than at baseline for the delayed intervention group. Overall asthma severity scores did not change. However, the median functional severity score (FSS) component of the severity score improved more in the intervention group (33% vs. 20%) than in the delayed intervention group. At the study's end, the median FSSs for the intervention group improved 25% compared with the delayed intervention group, (p<0.01). Differences between groups for medication use, emergency department (ED) visits or hospitalization were not significant.
Conclusions:
Despite low retention, the intervention resulted in decreased dust mite allergen levels and increased FSSs among the intervention group. The interventions probably contributed to the improvements, especially among the more severely affected children. This study highlights the complexities of designing and assessing the outcomes from a multifaceted asthma intervention.
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