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Related Experiment Videos

Ocular changes with oxaliplatin.

Denise O'Dea1, Catherine M Handy, Ann Wexler

  • 1St. Vincent's Comprehensive Cancer Center, New York, NY, USA. dodea@aptiumoncology.com

Clinical Journal of Oncology Nursing
|May 20, 2006
PubMed
Summary
This summary is machine-generated.

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Oxaliplatin chemotherapy can cause rare but reversible vision problems, including tunnel vision and visual loss. Clinicians should monitor patients for these unusual ocular toxicities.

Area of Science:

  • Oncology
  • Ophthalmology
  • Neuro-oncology

Background:

  • Chemotherapeutic agents, including platinum compounds, can cause ocular toxicity.
  • Oxaliplatin is a widely used platinum compound in cancer treatment.

Observation:

  • This report details four patients experiencing ocular symptoms during oxaliplatin therapy.
  • Symptoms included tunnel vision and visual loss, particularly with postural changes.

Findings:

  • One patient presented with papilledema, an objective sign of increased intracranial pressure.
  • All reported ocular side effects were reversible upon discontinuation or management of oxaliplatin treatment.

Implications:

  • Clinicians must remain vigilant for rare ocular toxicities associated with oxaliplatin.

Related Experiment Videos

  • Early recognition and management of these visual disturbances are crucial for patient care.