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Updated: Jul 28, 2026

Polyelectrolyte Complex for Heparin Binding Domain Osteogenic Growth Factor Delivery
Published on: August 22, 2016
Heparan sulphate requirement in platelet-derived growth factor B-mediated pericyte recruitment
1Department of Medical Biochemistry and Microbiology, The Biomedical Center, Uppsala University, Sweden. Sindhulakshmi.kurup@imbim.uu.se
Abstract:
HS (heparan sulphate) plays a key role in angiogenesis, by interacting with growth factors required in the process. It has been proposed that HS controls the diffusion, and thus the availability, of platelet-derived growth factor B that is needed for pericyte recruitment around newly formed capillaries. The present paper summarizes our studies on the importance of HS structure in this regulatory process.
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