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Updated: Aug 8, 2026

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

[Causes and outcomes of coronary arteries perforations]

A Vural, I V Pershukov, T A Batyraliev

    Kardiologiia
    |May 20, 2006
    PubMed

    Insights

    Coronary artery perforation during percutaneous coronary intervention is rare but serious. Outcomes improved over time, with declining rates of adverse events and mortality, suggesting enhanced procedural safety.

    Area of Science:

    • Cardiology
    • Interventional Cardiology
    • Vascular Medicine

    Context:

    • Percutaneous coronary interventions (PCI) are common procedures for treating coronary artery disease.
    • Coronary artery perforation (CAP) is a rare but significant complication of PCI.
    • Understanding CAP predictors and outcomes is crucial for improving patient safety.

    Purpose:

    • To evaluate in-hospital and long-term outcomes of patients experiencing coronary artery perforation during PCI.
    • To identify predictors associated with the occurrence of coronary artery perforation.
    • To analyze trends in CAP rates and associated adverse events over time.

    Summary:

    • A study of 127 patients (1.08% of PCI cases) who experienced coronary artery perforation between 1997 and 2002.
    • Identified predictors included complex stenoses, chronic occlusions, calcified lesions, small vessel lumen, and specific devices (excimer laser, thromboextractor).
    • Observed a decline in perforation rates, cardiac tamponade, urgent coronary artery bypass surgery, and mortality throughout the study period.

    Impact:

    • Demonstrates a trend towards improved safety in PCI procedures, with reduced complication rates.
    • Highlights key factors contributing to coronary artery perforation, aiding in risk stratification and prevention strategies.
    • Provides valuable data for interventional cardiologists to refine techniques and patient selection for PCI.

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