Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release

Davide Quarta1, Francisco Ciruela, Kshitij Patkar

  • 1Behavioral Neuroscience Branch, National Institute on Drug Abuse, IRP, NIH, DHHS, Baltimore, MD 21224, USA.

Summary

Dopamine D(2) autoreceptors and nicotinic acetylcholine (nACh) receptors interact on nerve terminals. These receptors form complexes that modulate dopamine release in the striatum, revealing crosstalk between receptor types.

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