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Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
Epstein Barr virus hepatitis: case series and review
1Department of Internal Medicine, Infectious Diseases Division, Naval Medical Center San Diego, San Diego, CA 92134-1005, USA. NFCrum@nmcsd.med.navy.mil
Southern Medical Journal
|May 23, 2006
Summary
Epstein Barr virus (EBV) infection often causes unrecognized liver enzyme abnormalities. This review highlights EBV
Area of Science:
- Hepatology
- Virology
- Gastroenterology
Background:
- Epstein Barr virus (EBV) is a common human herpesvirus.
- EBV infection typically presents asymptomatically.
- Subclinical liver enzyme abnormalities occur in 80-90% of EBV cases.
Observation:
- Acute EBV infection can manifest as cholestatic hepatitis with jaundice.
- Hepatitis with moderate transaminase elevation is also observed.
- Gastrointestinal complications include splenic rupture and liver failure.
Findings:
- EBV can lead to clinically significant hepatitis.
- The article reviews EBV-associated gastrointestinal complications.
- Potential links to autoimmune hepatitis and hepatocellular carcinoma are discussed.
Implications:
- Increased awareness of EBV's hepatic manifestations is crucial.
- Early recognition can prevent severe liver complications.
- Further research into EBV's role in chronic liver disease and cancer is warranted.
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