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Published on: September 5, 2016
[Advances in studies on active components and monomes of the traditional Chinese medicine targeted platelet]
Xiu-li Shi1, Jia Fu, Guang-wu Li
1The First Affiliated Hospital of Anhui Medical University, Hefei, China. shixiuli2000@yahoo.com.cn
Insights
Active components from traditional Chinese medicine target platelet functions to prevent and treat ischemic cardiovascular and cerebrovascular diseases. This summary provides references for future drug development and clinical use.
Area of Science:
- Pharmacology
- Traditional Chinese Medicine
- Cardiovascular Research
Context:
- Ischemic cardiovascular and cerebrovascular diseases pose significant health challenges.
- Platelet activation, adhesion, and aggregation are key mechanisms in thrombosis.
- Traditional Chinese Medicine (TCM) offers potential therapeutic agents.
Purpose:
- To summarize the effects of TCM active components and monomers on platelet activity.
- To highlight their role in preventing and treating ischemic diseases.
- To provide a reference for drug discovery and clinical applications.
Summary:
- Active components and monomers from TCM inhibit platelet activation, adhesion, and aggregation.
- These actions directly target the mechanisms of thrombosis.
- This approach is effective in preventing and treating ischemic cardiovascular and cerebrovascular diseases.
Impact:
- Offers a basis for developing novel anti-thrombotic therapies.
- Facilitates the investigation of TCM for cardiovascular and cerebrovascular conditions.
- Supports the integration of TCM into modern medical practice for ischemic diseases.
Abstract:
These active components and monomes inhibit thrombosis aimed directly at activation, adhesiveness and aggregation of platelet, thus preventing and curing ischemic cardiovascular and cerebrovascular diseases. Here we summarized the effect of active components and monomes of the traditional Chinese medicine targeted platelet on ischemic cardiovascular and cerebrovascular diseases, to provide references for drug investigation and clinical application.
