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From gut homeostasis to cancer

Freddy Radtke1, Hans Clevers, Orbicia Riccio

  • 1Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland. Freddy.Radtke@isrec.unil.ch

Current Molecular Medicine
|May 23, 2006
PubMed
Summary

The intestine constantly renews itself, controlled by developmental pathways like Wnt and Notch. Deregulation of these pathways contributes to colorectal cancer development.

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