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Experimental Analysis of Apoptotic Thymocyte Engulfment by Macrophages
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A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis

Sudhir Gupta1, Anshu Agrawal, Sudhanshu Agrawal

  • 1Laboratory of Cellular Immunology, Division of Basic and Clinical Immunology, University of California, Irvine, California 92697, USA. sgupta@uci.edu

Immunity & Ageing : I & A
|May 23, 2006
PubMed

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Cells respond to damage and stress through highly coordinated processes that decide whether they survive or undergo controlled self-destruction. Two major pathways involved in this regulation are apoptosis, a type of programmed cell death, and autophagy, a survival mechanism that helps cells adapt to adverse conditions.ApoptosisApoptosis removes aged or injured cells to maintain tissue balance. During this process, the cell shrinks, chromatin condenses and fragments, and membrane-bound...
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