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Progress towards eliminating lymphatic filariasis in Zanzibar: a model programme
Khalfan A Mohammed1, David H Molyneux, Marco Albonico
1Programme Manager Ministry of Health and Social Welfare, PO Box 236, Zanzibar, United Republic of Tanzania.
Trends in Parasitology
|May 23, 2006
Summary
Lymphatic filariasis elimination programs in Zanzibar utilized mass drug administration (MDA) with albendazole and ivermectin. This strategy successfully reduced Wuchereria bancrofti prevalence and intensity, offering a model for global elimination efforts.
Area of Science:
- Tropical Medicine
- Infectious Diseases
- Public Health
Background:
- Lymphatic filariasis (LF) poses a significant global health burden.
- Mass drug administration (MDA) is a key strategy for LF elimination.
- Sub-Saharan Africa has numerous LF endemic countries.
Purpose of the Study:
- To evaluate the success of LF elimination programs in Zanzibar.
- To identify critical factors contributing to the program's effectiveness.
- To provide a model for other countries undertaking LF elimination.
Main Methods:
- Completion of five rounds of mass drug administration (MDA).
- Combination therapy using albendazole and ivermectin.
- Community-based drug distribution and morbidity management.
Main Results:
- Zanzibar successfully completed five rounds of MDA, becoming the first in Africa to do so.
- Significant reduction in the prevalence and intensity of Wuchereria bancrofti.
- Identification of key success factors including political commitment and community involvement.
Conclusions:
- The Zanzibar LF elimination program demonstrates the efficacy of MDA with albendazole and ivermectin.
- Political will, social mobilization, and community engagement are vital for successful LF elimination.
- The Zanzibar model provides valuable insights for global LF control strategies.