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Updated: Jul 31, 2026

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
Published on: February 24, 2016
Clinical experience with Alloderm: a one-staged composite dermal/epidermal replacement utilizing processed cadaver
R A Callcut1, M J Schurr, M Sloan
1Department of Surgery, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA.
Unlabelled:
Alloderm has been advocated for the management of acute burns. However, few studies have demonstrated the feasibility of this technique.
Methods:
We reviewed the medical records of all patients treated in our burn center who received Alloderm since 1999.
Results:
Alloderm was used in 21 burn patients and 6 patients with traumatic skin loss. The average size of Alloderm used in the burn patients was 517+/-144 cm(2) (range 24-3000 cm(2)). The average Alloderm thickness used was 0.008 in. and autografts were harvested at an average of 0.007 in. Overall, Alloderm was used in a variety of locations including the face in 3 patients (2 burns, 1 traumatic skin loss) and hands in 7 patients (6 burns, 1 traumatic skin loss). Successful take was observed in 26/27 patients.
Conclusions:
Alloderm can be used successfully in patients with acute burns requiring grafting.

