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[Reference values for anaemia in the elderly].

R G J Westendorp¹, G J Izaks

¹Universitair Medisch Centrum Groningen, afd. Algemene Interne Geneeskundel Geriatrie, Postbus 30.001, 9700 RB Groningen.

Nederlands Tijdschrift Voor Geneeskunde

|May 24, 2006

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Anemia in older adults is not a normal part of aging and is linked to higher mortality and functional decline. The World Health Organization (WHO) guidelines for anemia apply to all age groups.

Area of Science:

Gerontology
Hematology

Context:

Lower hemoglobin (Hb) reference values are often applied to older patients, assuming decreased Hb is physiological with aging.
However, Hb levels below World Health Organization (WHO) guidelines are associated with increased mortality in older individuals.

Purpose:

To determine if the WHO reference values for anemia are applicable to older adults.
To investigate the association between decreased Hb levels and mortality and functional impairments in the elderly.

Summary:

Anemia, defined by WHO Hb levels (< 8.1 mmol/l for men, < 7.5 mmol/l for women), is not physiological in older adults.
Diagnostic tests reveal causes for anemia in over 80% of elderly anemic patients.
Decreased Hb levels, even if only slightly below WHO values, correlate with increased mortality and functional impairments like mobility disorders.

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Impact:

The WHO reference values for anemia are valid for older individuals.
Recognizing and treating anemia in older adults is crucial for improving health outcomes and reducing mortality.
This challenges the notion that lower Hb levels are normal in aging, emphasizing the need for further diagnostic evaluation.