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Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
Published on: March 10, 2020
The epidemiology of antibiotic resistance in Campylobacter
John E Moore1, Mary D Barton, Iain S Blair
1Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK. jemoore@niphl.dnet.co.uk
Microbes and Infection
|May 24, 2006
Summary
Global antibiotic resistance in thermophilic campylobacters, like Campylobacter jejuni and C. coli, is a growing concern. This review explores resistance epidemiology, rates, surveillance, and environmental factors impacting treatment for humans and animals.
Area of Science:
- Microbiology
- Veterinary Medicine
- Public Health
Background:
- Antibiotic resistance in thermophilic campylobacters (e.g., Campylobacter jejuni, C. coli) is a significant global issue.
- Fluoroquinolone and macrolide resistance are particularly concerning for human and animal health.
- Understanding resistance acquisition and transmission is crucial for effective treatment strategies.
Purpose of the Study:
- To review the clinical epidemiology of antibiotic resistance in human and animal thermophilic campylobacters.
- To provide an update on global antibiotic resistance rates in these bacteria.
- To examine the role of the environment and biocides in antimicrobial resistance.
Main Methods:
- Literature review focusing on clinical epidemiology.
- Analysis of global antibiotic resistance rates.
- Examination of surveillance data from animal sources, especially poultry.
- Investigation of environmental factors and biocide resistance.
Main Results:
- Antibiotic resistance is widespread globally in thermophilic campylobacters.
- Poultry serves as a significant reservoir and source for resistant strains.
- Environmental contamination plays a role in the spread of resistant campylobacters.
- Co-resistance to biocides is also a noted issue.
Conclusions:
- Urgent strategies are needed to combat rising antibiotic resistance in Campylobacter species.
- Integrated surveillance and control measures across human, animal, and environmental sectors are essential.
- Further research into resistance mechanisms and transmission pathways is warranted.
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