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Updated: Aug 8, 2026
09:43
Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons
Published on: May 25, 2015
Phrenic neuropathy due to neuralgic amyotrophy
Bryan E Tsao1, Denis A Ostrovskiy, Asa J Wilbourn
1Department of Neurology, The Cleveland Clinic, Cleveland, OH 44195, USA. tsaob@ccf.org
Neurology
|May 24, 2006
Summary
Idiopathic phrenic neuropathy may often be caused by neuralgic amyotrophy. A review of 33 patients found 17 had neuralgic amyotrophy, suggesting this is a common underlying condition.
Area of Science:
- Neurology
- Nerve Disorders
Background:
- Idiopathic phrenic neuropathy presents a diagnostic challenge.
- Understanding its underlying causes is crucial for effective patient management.
Purpose of the Study:
- To investigate the potential link between idiopathic phrenic neuropathy and neuralgic amyotrophy.
- To determine the prevalence of neuralgic amyotrophy in patients with isolated phrenic neuropathy.
Main Methods:
- Retrospective review of medical records for 33 patients diagnosed with idiopathic phrenic neuropathy.
- Clinical assessment and electrodiagnostic evaluations were analyzed.
Main Results:
- Out of 33 patients, 17 (51.5%) exhibited clinical features consistent with neuralgic amyotrophy.
- This suggests a significant overlap between the two conditions.
Conclusions:
- Neuralgic amyotrophy should be considered a potential causative disease in patients presenting with apparently isolated phrenic neuropathy.
- Comprehensive clinical and electrodiagnostic assessments are vital for accurate diagnosis.
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