Related Experiment Videos
Changes in transglutaminase activity in carbon tetrachloride-damaged rat liver
H Kohno1, K Kashimura, S Katoh
1Department of Radiopharmacy, Tohoku College of Pharmacy, Miyagi, Japan.
Experientia
|January 15, 1991
Abstract:
A significant decrease in transglutaminase (TGase) activity was observed in the cytosol and nuclear fractions of carbon tetrachloride-damaged rat liver. The degree of decrease in TGase activity in the cytosol fraction was closely related to the serum transaminase level. Gel filtration studies revealed that TGase activity in 80 kDa fractions significantly decreased, but that in 160 kDa fractions slightly increased after carbon tetrachloride treatment.