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Updated: Aug 8, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Giant mesenteric fibromatosis presenting as small bowel obstruction
Stefan Holubar1, Amit J Dwivedi, James O'Connor
1Department of Surgery, North Shore University/Long Island Jewish Medical Center, Manhasset, New York, USA.
Abstract:
Mesenteric fibromatosis is a proliferative fibroblastic neoplasia of the small intestine mesentery that may occur as a unique or multiple formation. Mesenteric fibromatosis is a rare, locally aggressive neoplasm and may present with abdominal discomfort, abdominal pain, weight loss, or symptoms of ureteral obstruction, mesenteric ischemia, or intestinal obstruction. It is of the utmost importance to distinguish mesenteric fibromatosis from gastrointestinal stromal tumors. Histopathology accurately differentiates between these two distinct entities. The preferred treatment is local surgical excision with a margin of uninvolved tissue. The involvement of important structures like the superior mesenteric artery and the superior mesenteric vein may pose a challenge during resection, but these tumors can be excised and the vessels repaired primarily.
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