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Updated: Aug 8, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Coronary artery stenosis
1London Chest Hospital, Bonner Road, London E2 9JX, UK. ian.weir@mac.com
Insights
Percutaneous coronary intervention (PCI) is rising, impacting coronary artery bypass grafting (CABG) referrals. Evidence suggests CABG remains superior for complex coronary artery disease, but long-term data is needed.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Technology Assessment
Background:
- The increasing use of percutaneous coronary intervention (PCI) has led to a decline in coronary artery bypass grafting (CABG) referrals, creating a crisis in cardiac surgery.
- This shift raises questions about the future of CABG, a historically successful surgical procedure.
- The implications extend to healthcare service provision, surgical training, and informed patient consent.
Purpose of the Study:
- To present the arguments for the increasing pre-eminence of PCI in treating coronary artery disease.
- To critically evaluate the evidence base comparing PCI and CABG, particularly for complex coronary artery disease.
- To advocate for a multidisciplinary approach in selecting treatment options for patients with coronary artery disease.
Main Methods:
- Review and synthesis of existing data and evidence comparing PCI and CABG.
- Analysis of the strengths and weaknesses of current comparative studies.
- Presentation of arguments from proponents of both PCI and CABG.
Main Results:
- Percutaneous coronary intervention (PCI) has seen exponential growth in treating coronary artery disease.
- Evidence strongly favors coronary artery bypass grafting (CABG) for triple vessel and left main coronary disease.
- Concerns exist regarding the lack of long-term outcome data for PCI and methodological limitations in comparative studies.
Conclusions:
- The dominance of PCI over CABG is increasing, but its long-term validity requires further investigation.
- Further evidence is needed to determine if the current trend of PCI dominance over CABG will be vindicated.
- A multidisciplinary approach to patient treatment options is advocated, but its implementation remains uncertain.
Abstract:
The near exponential rise in percutaneous coronary intervention(PCI) in the treatment of patients with coronary artery disease and the consequent decline in referral of patients for coronary artery bypass grafting (CABG) has lead to a crisis in cardiac surgery. Is CABG, one of the most successful and widely applied surgical procedures, about to follow surgery for peptic ulcer disease into obsolescence? The question has serious implications for service provision and training as well as for informed patient consent. Keith Dawkins puts the case for PCI and gives a very clear and concise account of its inexorable rise to pre-eminence. David Taggart has taken on the Goliath of interventional cardiology and its associated industry by persuasively marshalling the data from the evidence base which strongly favours surgery in triple vessel and left main coronary disease. He points to the lack of long-term results and also to the weaknesses of many of the comparative studies so far published. His arguments have been positively received on both sides of the Atlantic but it is by no means certain that they will bring about the multidisciplinary approach to providing patients with treatment options which he and others advocate. It also remains to be seen whether the evidence base when it is eventually acquired will vindicate the present increasing dominance of PCI over CABG.
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