Related Experiment Video
Updated: Aug 8, 2026
08:38
Extraction and Analysis of Cortisol from Human and Monkey Hair
Published on: January 24, 2014
Corticotropin-releasing hormone in nonhuman primates
1Department of Psychology, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Victoria 3800, Australia. jillian.broadbear@med.monash.edu.au
Summary
Corticotropin-releasing hormone (CRH) influences behavior and physiology throughout life. Research in nonhuman primates reveals CRH
Area of Science:
- Neuroendocrinology
- Primate Behavior
- Reproductive Biology
Background:
- Corticotropin-releasing hormone (CRH) is crucial for physiological and behavioral responses.
- Nonhuman primates are vital models for studying CRH due to genetic relatedness.
Purpose of the Study:
- To review CRH research in nonhuman primates.
- To explore CRH's roles across the lifespan and in various functions.
Main Methods:
- Literature review of studies on CRH in monkeys and apes.
- Analysis of CRH and receptor distribution.
- Examination of CRH's involvement in fertility, stress, appetite, and immunity.
Main Results:
- CRH impacts fertility, pregnancy, and parturition.
- Early-life stress shapes behavior and neural processes via CRH.
- CRH regulates appetitive behaviors and immune responses.
Conclusions:
- Nonhuman primate research provides key insights into CRH's role in social behavior and parenting.
- Understanding CRH is fundamental to comprehending human behavior and physiology.
Related Concept Videos
01:19Cushing Syndrome II: Pathophysiology
Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
01:26Cushing Syndrome I: Introduction
Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the syndrome.Exogenous...