Emerging possibilities in the development and function of regulatory T cells

Kajsa Wing1, Zoltán Fehérvári, Shimon Sakaguchi

  • 1Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Shogoin 53, Kawahara-cho, Sakyoku, Kyoto 606-8507, Japan. kajsa@frontier.kyoto-u.ac.jp

Summary

CD25+CD4+ Regulatory T cells (Treg) are crucial for immune suppression in areas like self-tolerance and transplantation. This review addresses current knowledge gaps in Treg development and function, highlighting ongoing research directions.