Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Serum parameters, inflammation, renal function and patient outcome.

Wai-Kei Lo1

  • 1Department of Medicine, Tung Wah Hospital, Hong Kong, SAR, China.

Contributions to Nephrology
|May 25, 2006
PubMed
Summary

Early markers like albumin and prealbumin may indicate inflammation rather than nutrition, impacting patient survival. Residual renal function is also a key predictor, with its link to inflammation gaining attention.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Term Effects of Sevelamer on Vascular Calcification, Arterial Stiffness, and Calcification Propensity in Patients Receiving Peritoneal Dialysis: The Randomized Pilot SERENE (Sevelamer on Vascular Calcification, Arterial Stiffness) Trial.

Kidney medicine·2022
Same author

The challenge of patient empowerment in hand hygiene promotion in health care facilities in Hong Kong.

American journal of infection control·2017
Same author

Epidemiology and Clinical Characteristics of <i>Acinetobacter</i> Peritoneal Dialysis-Related Peritonitis in Hong Kong-With a Perspective on Multi-Drug and Carbapenem Resistance.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2016
Same author

Corrigendum to "Carriage niches and molecular epidemiology of Staphylococcus lugdunensis and methicillin-resistant S. lugdunensis among patients undergoing long-term renal replacement therapy". Diagnostic microbiology and infectious disease 81(2015) 141-144.

Diagnostic microbiology and infectious disease·2016
Same author

Emergence of ileS2-Carrying, Multidrug-Resistant Plasmids in Staphylococcus lugdunensis.

Antimicrobial agents and chemotherapy·2016
Same author

Ischaemic stroke in patients with atrial fibrillation with chronic kidney disease undergoing peritoneal dialysis.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2015

Area of Science:

  • Biochemistry
  • Clinical Medicine
  • Nephrology

Background:

  • Early serum parameters such as albumin and prealbumin were traditionally viewed as indicators of nutritional status.
  • Emerging evidence highlights the significant role of inflammation in malnutrition, cardiovascular disease, and mortality.
  • C-reactive protein is recognized as a potent predictor of patient mortality.

Purpose of the Study:

  • To re-evaluate the role of early serum markers in predicting patient outcomes.
  • To explore the relationship between inflammation and nutritional markers.
  • To investigate the connection between residual renal function and inflammation.

Main Methods:

  • Analysis of early serum parameters (albumin, prealbumin, C-reactive protein).
  • Assessment of patient outcomes and mortality predictors.
  • Evaluation of residual renal function in patient cohorts.

Main Results:

  • Albumin and prealbumin, initially considered nutritional markers, likely reflect inflammatory processes.
  • C-reactive protein strongly predicts mortality.
  • Residual renal function is a significant predictor of patient outcomes.

Conclusions:

  • Inflammation plays a crucial role in patient outcomes, potentially overshadowing nutritional status as indicated by early serum markers.
  • The interplay between preserving residual renal function and managing inflammation is a critical area for future research in patient care.

Related Experiment Videos