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Updated: Aug 8, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
14:19

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction

Published on: June 29, 2013

Perinatal outcome and later implications of intrauterine growth restriction

Eugenia K Pallotto1, Howard W Kilbride

  • 1Children's Mercy Hospitals and Clinics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri 64108, USA.

Clinical Obstetrics and Gynecology
|May 25, 2006
PubMed

Insights

Infants born with intrauterine growth retardation (IUGR) or small-for-gestation-age (SGA) face higher risks of mortality and birth complications. These growth issues can lead to long-term health and developmental challenges in childhood.

Area of Science:

  • Neonatal Health
  • Pediatric Outcomes
  • Developmental Pediatrics

Background:

  • Intrauterine growth retardation (IUGR) and small-for-gestation-age (SGA) status affect infant health.
  • These conditions pose significant risks during the perinatal period and beyond.

Observation:

  • Infants with IUGR/SGA are prone to perinatal mortality and birth adaptation issues like acidosis and hypoglycemia.
  • Complications of prematurity, such as chronic lung disease and necrotizing enterocolitis, are also prevalent.

Findings:

  • Childhood implications include short stature, cognitive delays, and increased risk of neurologic disorders like cerebral palsy.
  • Low socioeconomic status exacerbates IUGR risks and is linked to long-term disabilities.

Implications:

  • Preterm delivery morbidities add to fetal growth restriction issues, increasing neurodevelopmental risks.
  • Early identification and management of IUGR/SGA are crucial for mitigating long-term adverse outcomes.

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