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Trisomy 21 and the pediatric surgeon

Michael J Allshouse1

  • 1Pediatric Surgery, The Children's Hospital, Denver, Colorado 80218, USA. Allshouse.Michael@tchden.org

Current Opinion in Pediatrics
|May 25, 2006
PubMed

Insights

Pediatric surgical care for children with Down syndrome (Trisomy 21) has advanced, offering improved quality of life. Surgical outcomes for anomalies are now comparable to typical children, fostering optimism.

Area of Science:

  • Pediatric Surgery
  • Genetics
  • Developmental Pediatrics

Background:

  • Trisomy 21 (Down syndrome) presents unique challenges in pediatric surgery.
  • Historically, surgical interventions for certain anomalies were considered futile.
  • Advances now offer viable treatment options, improving quality of life.

Purpose of the Study:

  • To review the current state of surgical treatment for anomalies in children with Down syndrome.
  • To highlight the importance of a multidisciplinary team approach.
  • To emphasize the evolving understanding of Trisomy 21 pathophysiology in surgical contexts.

Main Methods:

  • Review of current surgical techniques and outcomes for pediatric patients with Down syndrome.
  • Analysis of associated medical conditions impacting surgical care.
  • Evaluation of anesthetic considerations and post-operative management.

Main Results:

  • Surgical outcomes for colorectal anomalies in children with Down syndrome are nearly equivalent to those in typical children.
  • Children with Down syndrome experience benefits from surgical techniques equally.
  • Associated conditions include autoimmune disorders, increased susceptibility to infections and malignancy, anesthetic complications, and aerodigestive tract issues.

Conclusions:

  • Optimism surrounds surgical treatment for children with Down syndrome due to improved techniques and anesthetic management.
  • Recognizing Trisomy 21-specific issues enhances surgical safety and ethical considerations.
  • Enhanced quality of life and societal integration are key outcomes.
Abstract

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