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Updated: Aug 8, 2026

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
Published on: March 15, 2024
[Splenic abscess: presentation of nine cases]
Iago Villamil-Cajoto1, F L Lado, A Van den Eynde-Collado
1Departamento de Medicina, Servicio de Medicina Interna, Hospital Clínico Universitario de Santiago de Compostela, Spain. iago.villamil.cajoto@sergas.es
Abstract:
Relatively rare, splenic abscess is difficult to diagnose and often fatal if left untreated. The disease is thought to be growing in frequency because of the increasing number of inmunocompromised patients. Several mechanisms for the development of splenic abscess may exist. Some studies demonstrate that prior splenic injury in addition to bacteraemia is required for a splenic abscess to occur. In our series, 9 non immunocompromised patients were identified to have this disease during a 6 years period. Pathogens isolated included Salmonella sp, Staphylococcus sp and Enterococcus sp. Splenectomy was performed in three patients; in another a percutaneous drainage was done. One patient died. In summary, though rare, splenic abscess presents with high morbidity and mortality. In our experience, risk factors as immunocompromise seem not to be so prevalent in patients with splenic abscess and therefore this diagnosis should be considered in all patients with fever of unknown origin.
Insights
Splenic abscess is a rare but serious condition. Our findings suggest immunocompromise may not be as prevalent, emphasizing its consideration in fever of unknown origin cases.
Area of Science:
- Infectious Diseases
- Abdominal Surgery
Context:
- Splenic abscess is a rare condition with high mortality.
- Increasing incidence is often attributed to immunocompromised patients.
- Diagnosis can be challenging, necessitating a high index of suspicion.
Purpose:
- To analyze the clinical characteristics and outcomes of splenic abscess.
- To evaluate the role of immunocompromise as a risk factor.
- To highlight the importance of considering splenic abscess in unexplained fever.
Summary:
- A series of 9 non-immunocompromised patients with splenic abscess over 6 years.
- Common pathogens included Salmonella, Staphylococcus, and Enterococcus.
- Treatment involved splenectomy or percutaneous drainage, with one mortality.
Impact:
- Challenges the assumption that immunocompromise is the primary risk factor for splenic abscess.
- Suggests splenic abscess should be considered in a broader patient population presenting with fever of unknown origin.
- Highlights the significant morbidity and mortality associated with splenic abscess, even in non-immunocompromised individuals.
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