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Related Experiment Videos

Herpes simplex keratitis following excimer laser application.

Chao-Kung Lu1, Ko-Hua Chen, Shui-Mei Lee

  • 1Department of Ophthalmology, Taipei Veterans General Hospital, Taiwan, ROC.

Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|May 26, 2006
PubMed
Summary
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Excimer laser procedures may trigger herpes simplex keratitis in susceptible individuals. Prompt antiviral treatment led to healing in two reported cases, suggesting a link between the laser and viral reactivation.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Surgical Technology

Background:

  • Herpes simplex keratitis (HSK) is a common cause of corneal blindness.
  • Ocular procedures can potentially trigger latent viral infections.

Purpose of the Study:

  • To present two cases of HSK following excimer laser refractive surgery.
  • To investigate the potential association between excimer laser use and HSK development.

Main Methods:

  • Two immunocompetent patients without prior ocular viral infection history were analyzed.
  • Cases involved excimer laser applications: LASIK and phototherapeutic keratectomy (PTK).

Main Results:

  • Both patients developed corneal ulcers post-procedure.

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  • Lesions resolved within 14 days after initiating antiviral therapy.

    • Conclusions:

    • The findings suggest a possible association between excimer laser use and herpes simplex virus reactivation.
    • Further research is warranted to understand this link and optimize patient management.