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The ATC (ataxia-telangiectasia complementation group C) locus localizes to 11q22-q23
1Department of Human Genetics, Sackler School of Medicine, Tel Aviv University, Israel.
Genomics
|February 1, 1991
Abstract:
The multisystem autosomal recessive disease ataxia-telangiectasia (A-T) is determined by several genes, as evidenced by the existence of four complementation groups in this disorder. Using linkage analysis, the ATA (A-T complementation group A) gene was previously localized to chromosome 11, region q22-q23. Analysis of the segregation of RFLP markers from this region in a Jewish-Moroccan family assigned to group C indicates that the ATC (A-T complementation group C) gene localizes to chromosome 11q22-q23 as well.