Related Experiment Video
Updated: Aug 8, 2026
05:22
Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Choroidal detachment in perforated corneal ulcers: frequency and management
R Singh1, T Umapathy, A Abedin
1Division of Ophthalmology and Visual Sciences, B Floor, Eye ENT Centre, Queens Medical Centre, Nottingham NG7 2UH, UK.
The British Journal of Ophthalmology
|May 26, 2006
Summary
Choroidal detachment (CD) is common in eyes with perforated corneal ulcers, especially larger ones. Cyanoacrylate glue effectively seals smaller perforations but requires monitoring for infection.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Ocular Imaging
Background:
- Perforated corneal ulcers pose a significant risk of vision loss.
- Choroidal detachment (CD) is a potential complication following corneal perforation.
- Cyanoacrylate glue is utilized for sealing corneal perforations.
Purpose of the Study:
- To determine the frequency of choroidal detachment (CD) in eyes with non-traumatic corneal ulcer perforation.
- To assess the efficacy and safety of cyanoacrylate glue in sealing corneal perforations.
Main Methods:
- A study of 18 eyes from 17 patients with non-traumatic perforated corneal ulcers.
- Ophthalmic examination including B-scan ultrasonography to detect CD.
- Assessment of cyanoacrylate glue efficacy and safety for corneal perforation repair.
Main Results:
- Choroidal detachment (CD) was observed in 44% of eyes (8/18).
- Larger perforations (>2 mm²) showed a higher incidence of CD (75%) compared to smaller ones (20%).
- Cyanoacrylate glue achieved a success rate of 87% (13/15 eyes), with re-gluing needed in 27% of successful cases.
Conclusions:
- Choroidal detachment is a frequent complication of corneal ulcer perforation, particularly in larger defects.
- Preoperative B-scan ultrasonography is recommended for large perforations to identify CD, which may necessitate drainage.
- Cyanoacrylate glue is effective and safe for small corneal perforations, but infection surveillance is crucial.
Related Concept Videos
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:28Esophageal Perforation-II: Clinical Manifestations and Management
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
01:23Ophthalmic Drug Delivery Systems
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
01:27Peptic Ulcer
Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the mucus...
01:17Pericarditis III: Medical Management
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...