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Ankle-arm index is a useful test for clinical practice in outpatients with suspected coronary artery disease

Shih-Tai Chang1, Chien-Lung Chen, Chi-Ming Chu

  • 1Division of Cardiology, Chiayi Chang Gung Memorial Hospital, Pu-TZ City, Chai Yi Hsien, Taiwan. cst1234567@yahoo.com.tw

Circulation Journal : Official Journal of the Japanese Circulation Society
|May 26, 2006
PubMed

Insights

The ankle-arm index (AAI) effectively predicts coronary artery disease (CAD) in outpatients. A low AAI (<0.9) indicates a higher likelihood of CAD in clinical practice.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Diagnostic Tools

Background:

  • A low ankle-arm index (AAI) is linked to cardiovascular mortality risk.
  • No prior data existed on AAI's utility for outpatients with suspected coronary artery disease (CAD).

Purpose of the Study:

  • To evaluate the effectiveness of the ankle-arm index (AAI) in predicting coronary artery disease (CAD) among outpatients in a clinical setting.

Main Methods:

  • 840 outpatients with suspected CAD underwent AAI measurements and coronary angiography.
  • Patients were categorized into Group A (AAI <0.9) and Group B (AAI ≥0.9).
  • Comparison of metabolic syndrome, obesity, hsCRP, and other clinical factors between groups.

Main Results:

  • Group A (n=191) had a higher prevalence of CAD (94.8%) compared to Group B (n=649, 78.4%).
  • Group A patients were older, had a higher female-to-male ratio, and exhibited higher rates of hypertension, diabetes, high LDL-cholesterol, and metabolic syndrome.
  • AAI was independently associated with metabolic syndrome (OR 1.769), high hsCRP (OR 3.907), and high uric acid (OR 2.580).

Conclusions:

  • The ankle-arm index (AAI) serves as an effective tool for predicting CAD in outpatients.
  • AAI measurement is a valuable addition to clinical practice for assessing CAD risk.
Abstract

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