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Related Experiment Videos

A cloudy bag and genital ulcers.

J Liesker1, A M van Elsacker-Niele, R Blanken

  • 1Department of Internal Medicine, Medical Center Leeuwvarden, The Netherlands.

Clinical Nephrology
|May 27, 2006
PubMed
Summary

A patient undergoing continuous peritoneal dialysis (CPPD) developed peritonitis and genital ulcers. Herpes simplex virus type 2 (HSV-2) infection was diagnosed, marking the first reported case of HSV-2 peritonitis in PD patients.

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Virology

Background:

  • Continuous peritoneal dialysis (CCPD) is a treatment for kidney failure.
  • Peritonitis is a common complication of peritoneal dialysis.
  • Culture-negative peritonitis presents a diagnostic challenge.

Observation:

  • A 30-year-old CCPD patient presented with genital ulcers and peritonitis.
  • Herpes simplex virus type 2 (HSV-2) was isolated from peritoneal fluid and genital lesions.
  • Serological tests confirmed a primary HSV-2 infection.

Findings:

  • This case represents the first documented instance of peritonitis caused by HSV-2 in a patient on peritoneal dialysis.
  • The findings suggest a potential link between genital herpes and peritonitis in PD patients.

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Implications:

  • Culture-negative peritonitis in PD patients may be attributed to recurrent or primary genital herpes infections.
  • This highlights the importance of considering viral causes, specifically HSV-2, in unexplained peritonitis.
  • Further investigation into HSV-2 as a cause of PD peritonitis is warranted.